Modifiable areal unit problem
The modifiable areal unit problem (MAUP) is a source of statistical bias that can significantly impact the results of statistical hypothesis tests. MAUP affects results when point-based measures of spatial phenomena are aggregated into districts, for example, population density or illness rates. The resulting summary values (e.g., totals, rates, proportions, densities) are influenced by both the shape and scale of the aggregation unit. For example, census data may be aggregated into county districts, census tracts, postcode areas, police precincts, or any other arbitrary spatial partition. Thus the results of data aggregation are dependent on the mapmaker's choice of which "modifiable areal unit" to use in their analysis. A census choropleth map calculating population density using state boundaries will yield radically different results than a map that calculates density based on county boundaries. Furthermore, census district boundaries are also subject to change over time, meaning the MAUP must be considered when comparing past data to current data. (Wikipedia).
