Sulfonium compounds

S-Adenosyl methionine

S-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. SAM was first discovered by Giulio Cantoni in 1952. In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis. In eukaryotic cells, SAM serves as a regulator of a variety of processes including DNA, tRNA, and rRNA methylation; immune response; amino acid metabolism; transsulfuration; and more. In plants, SAM is crucial to the biosynthesis of ethylene, an important plant hormone and signaling molecule. (Wikipedia).

S-Adenosyl methionine
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Aspirin to Acetaminophen - Part 6 of 6: Acetaminophen from p-aminophenol

This is the final part of the series, where the p-aminophenol is converted to the acetaminophen. Using acetic anhydride, the p-aminophenol is going to be acetylated. The reaction is carried out in water at room temperature. Acetic anhydride does react with water, but it happens slowly.

From playlist Aspirin to Acetaminophen (Parts 1 to 6)

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Special Cases in Fatty Acid Metabolism

MIT 5.07SC Biological Chemistry, Fall 2013 View the complete course: http://ocw.mit.edu/5-07SCF13 Instructor: John Essigmann Professor Essigmann explores several special cases in fatty acid metabolism in this video. This includes fatty acids that have a cis-double bond and fatty acids tha

From playlist MIT 5.07SC Biological Chemistry I, Fall 2013

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How to Convert Aspirin to Salicylic Acid (Base Hydrolysis Method)

In my previous video I described how to extract acetylsalicylic acid from Aspirin tablets. In this video, I will be hydrolyzing ester bond in the acetylsalicylic acid to form salicylic acid.

From playlist Syntheses and Demonstrations

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Lexicon of Biochemical Reactions: Cofactors Formed from Vitamin B12

MIT 5.07SC Biological Chemistry, Fall 2013 View the complete course: http://ocw.mit.edu/5-07SCF13 Instructor: JoAnne Stubbe Professor Stubbe refers to the cofactors formed from Vitamin B12 as "Nature's most spectacularly beautiful cofactors." These cofactors bind to the enzyme which plays

From playlist MIT 5.07SC Biological Chemistry I, Fall 2013

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Sn1 reactions introduction

Description More free lessons at: http://www.khanacademy.org/video?v=eB5NVPzBCzM

From playlist Substitution and elimination reactions | Organic Chemistry | Khan Academy

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REUPLOAD - Make 2-(p-chlorophenyl)-3-oxopentanenitrile - Step 5 in Pyrimethamine Synthesis

In this video we make 2-(p-chlorophenyl)-3-oxopentanitrile which is step 5 in our synthesis of Pyrimethamine Related videos: Drying alcohol: https://www.youtube.com/watch?v=NMfs3e9OdZQ Making sodium metal with domestically available chemicals: https://www.youtube.com/watch?v=jCrFFVVcPU

From playlist Pyrimethamine

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26. Chemical and Biological Oxidations

MIT 5.111 Principles of Chemical Science, Fall 2014 View the complete course: https://ocw.mit.edu/5-111F14 Instructor: Catherine Drennan Viewers are introduced to agents of oxidation and agents of reduction. Are oxidizing agents really that bad for you? Hear from Professor John Essigmann

From playlist MIT 5.111 Principles of Chemical Science, Fall 2014

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[TensorFlow 2 Deep Learning] RNN

https://github.com/minsuk-heo/tf2/blob/master/jupyter_notebooks/08.RNN.ipynb Understand RNN(recurrent neural network) and implement it using tensorflow 2. all machine learning youtube videos from me, https://www.youtube.com/playlist?list=PLVNY1HnUlO26x597OgAN8TCgGTiE-38D6

From playlist Machine Learning

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Make p-Chlorophenyl Acetonitrile - Step 4 in Pyrimethamine Synthesis

In this video we make p-chlorophenyl acetonitrile from the p-chlorobenzyl chloride and the sodium cyanide in a previous video. ( Complete pyrimethamine playlist so far: https://www.youtube.com/playlist?list=PLU79801KtVAU1XsTwHaKkqQoBgz_VYmPS ) Fortunately this is a very mild process and

From playlist Pyrimethamine

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Aspirin to Acetaminophen - Part 2 of 6: Conversion of ASA to Salicylic Acid

Hey guys, today we will be going over the second step in the quest to acetaminophen. In the previous video I extracted ASA from aspirin pills and now it is time to hydrolyze it to salicylic acid. This will be done by a simple acid-catalyzed ester hydrolysis. The next step in this process

From playlist Aspirin to Acetaminophen (Parts 1 to 6)

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Acylation of benzene || 3d Video Animation || Education

Acylation of benzene || 3d Video Animtaion || Education the mechanism for the c acyation of benzene involving an electrophilic substitution reaction between benzene and ethanoyl chloride in the presence of an aluminium chloride catalyst. The Friedel–Crafts acylation was first discovered i

From playlist Chemistry Topics

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36. Biochemistry

MIT 5.111 Principles of Chemical Science, Fall 2008 View the complete course: http://ocw.mit.edu/5-111F08 Instructor: Catherine Drennan, Elizabeth Vogel Taylor License: Creative Commons BY-NC-SA More information at http://ocw.mit.edu/terms More courses at http://ocw.mit.edu

From playlist MIT 5.111 Principles of Chemical Science, Fall 2008

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Lec 36 | MIT 5.111 Principles of Chemical Science, Fall 2005

Review (Prof. Catherine Drennan) View the complete course: http://ocw.mit.edu/5-111F05 License: Creative Commons BY-NC-SA More information at http://ocw.mit.edu/terms More courses at http://ocw.mit.edu

From playlist MIT 5.111 Principles of Chemical Science, Fall 2005

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10. Protein Folding 3

MIT 5.08J Biological Chemistry II, Spring 2016 Instructor: Elizabeth Nolan View the complete course: https://ocw.mit.edu/5-08JS16 YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP63vvR4xtexZdoPywRYIZI0- Professor Nolan presents the models for how GroEL/GroES facilitates

From playlist MIT 5.08J Biological Chemistry II, Spring 2016

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A Level Biology Revision "Translation".

In this video, we look at the process of translation. We start by exploring the features of the genetic code. I discuss how the genetic code works and how it is degenerate, non-overlapping and universal. Then we look at the role of transfer RNA in translation. Finally, I take you through t

From playlist A Level Biology "DNA, RNA and Protein Synthesis"

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10. Translation

MIT 7.016 Introductory Biology, Fall 2018 Instructor: Barbara Imperiali View the complete course: https://ocw.mit.edu/7-016F18 YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP63LmSVIVzy584-ZbjbJ-Y63 In today's lecture, Professor Imperiali covers the details of translati

From playlist MIT 7.016 Introductory Biology, Fall 2018

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Destroying 10 grams of tosyl azide

Here is an uncut video of quenching 10 grams of tosyl azide using acetylacetone and sodium hydroxide in water/acetonitrile followed by the decomposition of diazoacetone with sodium nitrite and sulfuric acid. I decided that storing tosyl azide which was over one year old was unsafe and tha

From playlist Rad Chemistry Experiments

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Introduction to Chemical Biology 128. Lecture 09: RNA part 2

UCI Chem 128 Introduction to Chemical Biology (Winter 2013) Lec 09. Introduction to Chemical Biology -- RNA -- Part 2 View the complete course: http://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html Instructor: Gregory Weiss, Ph.D. License: Creative Commons BY-NC-SA Ter

From playlist Chem 128: Week 5

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Acetaminophen/Paracetamol (Tylenol)

Acetaminophen, more commonly known by brand names such as Tylenol, is not a true NSAID, as it does not have anti-inflammatory properties. However, it is commonly discussed alongside NSAIDs as it has similar antipyretic and analgesic properties. Although its mechanism of action is not well-

From playlist Pharmacology

Related pages

Sulfonium | DNA | S-Adenosylmethioninamine