Chiral inversion is the process of conversion of one enantiomer of a chiral molecule to its mirror-image version with no other change in the molecule. Chiral inversion happens depending on various factors (viz. biological-, solvent-, light-, temperature- induced, etc.) and the energy barrier associated with the stereogenic element present in the chiral molecule. 2-Arylpropionic acid nonsteroidal anti-inflammatory drugs (NSAIDs) provide one of the best pharmaceutical examples of chiral inversion. Chirality is attributed to a molecule due to the presence of a stereogenic element (viz. center, planar, helical, or axis). Many pharmaceutical drugs are chiral and have a labile (configurationally unstable) stereogenic element. Chiral compounds with stereogenic center are found to have high energy barriers for inversion and generally undergo biologically mediated chiral inversion. While compounds with helical or planar chirality have low energy barriers and chiral inversions are often caused by solvent, light, temperature. When this happens, the configuration of the chiral molecule may rapidly change reversibly or irreversibly depending on the conditions. The chiral inversion has been intensively studied in the context of the pharmacological and toxicological consequences. Other than NSAIDs, chiral drugs with different chemical structures can also show this effect. Chiral drugs have different effects on the body depending on whether one enantiomer or both enantiomers act on different biological targets. As a result, chiral inversion can change how a pharmaceutical drug works in the body. From a pharmacological and toxicological point of view, it is very important to learn more about chiral inversion, the things that make it happen, and the tools used to figure out chiral inversion. (Wikipedia).
What is the difference between rotating clockwise and counter clockwise
👉 Learn how to rotate a figure and different points about a fixed point. Most often that point or rotation will be the original but it is important to understand that it does not always have to be at the origin. When rotating it is also important to understand the direction that you will
From playlist Transformations
Diffraction from Chirp Shaped Gratings
In this video, propagation of a normally incident wave through a chirp shaped grating is shown. The simulation utilized finite-difference time domain (FDTD) as the full wave solver. The chirp shape provides locally larger oscillations at the left end whereas it provides increasingly sma
From playlist Electromagnetic Animations
A physical pendulum finds stability in its inverted position when driven at the proper frequency and amplitude combination. The physical pendulum seen here is mounted on a ball-bearing pivot and can rotate 360 degrees; the pivot is driven at about 50 Hz with an amplitude of about 1 cm (3/
From playlist Oscillations and Waves
Physics - Mechanics: Torsion (1 of 14) What is Torsion?
Visit http://ilectureonline.com for more math and science lectures! In this video I will explain what is torsion and the variables associated with twisting of a steel rod. Next video in this series can be found at: https://youtu.be/jlt6Jy59nJs
From playlist PHYSICS 16.6 TORSION
B03 Simple harmonic oscillation
Explaining simple (idealised) harmonic oscillation, through a second-order ordinary differential equation.
From playlist Physics ONE
Electric Dipole Moment, Force, Torque, Potential Energy, Work, Electric Field, Physics
This physics video tutorial explains how to calculate the magnitude of the electric dipole moment and its direction. An electric dipole is simply the combination of a positive charge and a negative charge that have the same magnitude but opposite signs. This video shows you how to calcul
From playlist New Physics Video Playlist
AWESOME Electromagnetic force oscillation!!!
In this video i show electromagnetic force oscillation on a ruler. Also i demonstrate the standing wave on a ruler!
From playlist ELECTROMAGNETISM
Stereochemistry: Meso Compounds, Diastereomers
Meso soup! Here we will see how compounds with multiple stereocenters may be achiral overall, if they have an internal plane of symmetry (meso compounds) or an inversion center. In addition, we will define and discuss diastereomers. Now where's that soup... Watch the whole Organic Chemist
From playlist Organic Chemistry
Supersymmetric gauge theories (Lecture 3) by Shiraz minwalla
Statistical Physics Methods in Machine Learning DATE:26 December 2017 to 30 December 2017 VENUE:Ramanujan Lecture Hall, ICTS, Bengaluru The theme of this Discussion Meeting is the analysis of distributed/networked algorithms in machine learning and theoretical computer science in the "th
From playlist Kavli Asian Winter School (KAWS) on Strings, Particles and Cosmology 2018
The chiral matter by Dima Kharzeev
DISCUSSION MEETING TOPOLOGICAL ASPECTS OF STRONG CORRELATIONS AND GAUGE THEORIES (ONLINE) ORGANIZERS: Rob Pisarski (Brookhaven National Laboratory, USA), Sumathi Rao (HRI, India), Soeren Schlichting (Bielefeld University, Germany) and Sayantan Sharma (IMSc, India) DATE: 06 September 202
From playlist Topological aspects of strong correlations and gauge theories (ONLINE)
Determining clockwise vs counter clockwise rotations
👉 Learn how to rotate a figure and different points about a fixed point. Most often that point or rotation will be the original but it is important to understand that it does not always have to be at the origin. When rotating it is also important to understand the direction that you will
From playlist Transformations
Symmetry-broken topological phases by Tanmoy Das
DISCUSSION MEETING NOVEL PHASES OF QUANTUM MATTER ORGANIZERS: Adhip Agarwala, Sumilan Banerjee, Subhro Bhattacharjee, Abhishodh Prakash and Smitha Vishveshwara DATE: 23 December 2019 to 02 January 2020 VENUE: Ramanujan Lecture Hall, ICTS Bangalore Recent theoretical and experimenta
From playlist Novel Phases of Quantum Matter 2019
MagLab Theory Winter School 2019: Nandini Trivedi "Scientific Revolutions 1"
Topic: Scientific Revolutions: How can a gapless system be topological? The National MagLab held it's seventh Theory Winter School in Tallahassee, FL from January 7th - 11th, 2019.
From playlist 2019 Theory Winter School
Global chiral symmetry, extra dimensions, and topology (Lecture - 02) by David B Kaplan
Nonperturbative and Numerical Approaches to Quantum Gravity, String Theory and Holography DATE:27 January 2018 to 03 February 2018 VENUE:Ramanujan Lecture Hall, ICTS Bangalore The program "Nonperturbative and Numerical Approaches to Quantum Gravity, String Theory and Holography" aims to
From playlist Nonperturbative and Numerical Approaches to Quantum Gravity, String Theory and Holography
Physics - E&M: Magn Field Effects on Moving Charge & Currents (10 of 26) Magnetic Dipole Moment
Visit http://ilectureonline.com for more math and science lectures! In this video I will explain what is a magnetic dipole moment.
From playlist PHYSICS E&M 3: MAGNETIC FIELDS, MAGNETIC FORCES, MAGNETIC FIELD SOURCES, ELECTROMAGNETIC INDUCTION
Topological Phases and their Electromagnetic Responses by Joel Moore
COLLOQUIUM TOPOLOGICAL PHASES AND THEIR ELECTROMAGNETIC RESPONSES SPEAKER: Joel Moore (UC Berkeley and LBNL) DATE: Mon, 11 October 2021, 11:00 to 12:30 VENUE: Online Colloquium RESOURCES ABSTRACT This talk starts by reviewing known examples of how topological materials generate new
From playlist ICTS Colloquia
Chemistry 107. Inorganic Chemistry. Lecture 04
UCI Chemistry: Inorganic Chemistry (Fall 2014) Lec 04. Inorganic Chemistry -- Character Tables and One Application of Symmetry View the complete course: http://ocw.uci.edu/courses/chem_107_inorganic_chemistry.html Instructor: Matthew D. Law License: Creative Commons CC-BY-SA Terms of Use:
From playlist Chem 107: Week 2
Organic Chemistry 1 Exam 2 Review
This Organic Chemistry 1 Exam 2 Review covers stereochemistry, SN2 SN1 E1 E2 reactions, alkene reactions, and reactions of alkynes. Get The Full 3 Hour 44 Minute Video on Patreon: https://www.patreon.com/MathScienceTutor Direct Link to the Full Video: https://bit.ly/420cTys Download The
From playlist New Organic Chemistry Playlist
From playlist Trigonometry TikToks
Bootstrapping an N=2 fixed point by Pedro Liendo
Nonperturbative and Numerical Approaches to Quantum Gravity, String Theory and Holography DATE:27 January 2018 to 03 February 2018 VENUE:Ramanujan Lecture Hall, ICTS Bangalore The program "Nonperturbative and Numerical Approaches to Quantum Gravity, String Theory and Holography" aims to
From playlist Nonperturbative and Numerical Approaches to Quantum Gravity, String Theory and Holography