Tajima's D is a population genetic test statistic created by and named after the Japanese researcher Fumio Tajima. Tajima's D is computed as the difference between two measures of genetic diversity: the mean number of pairwise differences and the number of segregating sites, each scaled so that they are expected to be the same in a neutrally evolving population of constant size. The purpose of Tajima's D test is to distinguish between a DNA sequence evolving randomly ("neutrally") and one evolving under a non-random process, including directional selection or balancing selection, demographic expansion or contraction, genetic hitchhiking, or introgression. A randomly evolving DNA sequence contains mutations with no effect on the fitness and survival of an organism. The randomly evolving mutations are called "neutral", while mutations under selection are "non-neutral". For example, a mutation that causes prenatal death or severe disease would be expected to be under selection. In the population as a whole, the frequency of a neutral mutation fluctuates randomly (i.e. the percentage of individuals in the population with the mutation changes from one generation to the next, and this percentage is equally likely to go up or down) through genetic drift. The strength of genetic drift depends on population size. If a population is at a constant size with constant mutation rate, the population will reach an equilibrium of gene frequencies. This equilibrium has important properties, including the number of segregating sites , and the number of nucleotide differences between pairs sampled (these are called pairwise differences). To standardize the pairwise differences, the mean or 'average' number of pairwise differences is used. This is simply the sum of the pairwise differences divided by the number of pairs, and is often symbolized by . The purpose of Tajima's test is to identify sequences which do not fit the neutral theory model at equilibrium between mutation and genetic drift. In order to perform the test on a DNA sequence or gene, you need to sequence homologous DNA for at least 3 individuals. Tajima's statistic computes a standardized measure of the total number of segregating sites (these are DNA sites that are polymorphic) in the sampled DNA and the average number of mutations between pairs in the sample. The two quantities whose values are compared are both method of moments estimates of the population genetic parameter theta, and so are expected to equal the same value. If these two numbers only differ by as much as one could reasonably expect by chance, then the null hypothesis of neutrality cannot be rejected. Otherwise, the null hypothesis of neutrality is rejected. (Wikipedia).
囲碁★九路盤対局 -- TAS/lesson in 4:50 (+English captions)
ファミコン 囲碁★九路盤対局 (Igo Kyuu-Roban Taikyoku) 4分50秒 (レベル10) 2007年 9月20日 1回企及 http://tasvideos.org/1704S.html What is Go? Look here> https://bisqwit.iki.fi/jutut/go2.html
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TAS HD: Legend of Kage, The (NES) by Bisqwit in 05:36.97
Publication: http://tasvideos.org/595M.html This is a tool-assisted recording.
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Coalescence II: structured coalescent including pop structure....by Aneil Agrawal
Program Fourth Bangalore School on Population Genetics and Evolution ORGANIZERS: Deepa Agashe and Kavita Jain DATE: 27 January 2020 to 07 February 2020 VENUE: Ramanujan Lecture Hall, ICTS Bangalore No living organism escapes evolutionary change, and evolutionary biology thus connect
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Signatures of Selection by Shivansh Singhal
DISCUSSION MEETING SECOND PREPARATORY SCHOOL ON POPULATION GENETICS AND EVOLUTION ORGANIZERS Deepa Agashe (NCBS-TIFR, India) and Kavita Jain (JNCASR, India) DATE: 20 February 2023 to 24 February 2023 VENUE Madhava Lecture Hall, ICTS Bengaluru We plan an intensive 1-week preparatory school
From playlist SECOND PREPARATORY SCHOOL ON POPULATION GENETICS AND EVOLUTION
Plasma Based Particle Acceleration by Amita Das
06 March 2017 to 17 March 2017 VENUE: Ramanujan Lecture Hall, ICTS Bangalore Particle accelerators have been instrumental in unraveling some of the deep questions related to matter at the fundamental level, the latest being discovery of the Higgs Boson. The conventional accelerators, how
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Introduction to the coalescent theory - Lecture 1 by Magnus Nordborg
The Third Bangalore School on Population Genetics and Evolution DATE:05 March 2018 to 17 March 2018 VENUE:Ramanujan Lecture Hall, ICTS Bangalore. No living organism escapes evolutionary change. Evolutionary biology thus connects all biological disciplines. To understand the processes dri
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TAS Legend of Zelda Majora's Mask N64 in 134:03 by Mukki
http://tasvideos.org Played by I. Masterson aka. Mukki in 2:14:03.08. This is a tool-assisted speedrun. For further informations visit http://tasvideos.org/963M.html
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NES Super Mario Bros. TAS in 05:15.65 by Bisqwit
For more details, see http://tasvideos.org/665M.html This movie is the earliest attempt by Bisqwit (his 2nd version). It makes a number of mistakes and detours.
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NES Super Mario Bros TAS in 05:15.6 by Bisqwit
For more details, see http://tasvideos.org/664M.html This movie is the 2nd of Bisqwit's movies published (his 3rd attempt). It is a mere 3 frames faster than the previous version. This versions takes a number of detours such as playing with a koopa shell, getting a random coin, and takin
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TAS Final Fantasy 4 SNES in 173:14 by Deign
Tool-Assisted http://tasvideos.org Played in 2:53:14.37 by Robin Reigstad aka. Deign. This is a tool-assisted speedrun. For further informations visit http://tasvideos.org/1149M.html
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NES Castlevania TAS in 13:15.55 by Bisqwit
For more details, see http://tasvideos.org/674M.html This was the earliest Castlevania publication on TASVideos. It was one of the first tool-assisted speedruns to use damage boosting as a shortcut.
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Abandoned Stations: Grosvenor Road
A station so pointless, they built it twice. https://ko-fi.com/jagohazzard https://www.patreon.com/jagohazzard
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Some thoughts on plasma-based acceleration (PBA)...(Lecture - 01) by Warren Mori
06 March 2017 to 17 March 2017 VENUE: Ramanujan Lecture Hall, ICTS Bangalore Particle accelerators have been instrumental in unraveling some of the deep questions related to matter at the fundamental level, the latest being discovery of the Higgs Boson. The conventional accelerators, how
From playlist Laser Plasma Accelerator
MicroPython ESP32 Pwned Password Checker
I construct an inexpensive wireless device with an ILI9341 color touch screen to test passwords against the haveibeenpwned.com REST API using MicroPython and an ESP32. My full write-up for this project: https://www.rototron.info/projects/esp32-pwned-password-checker/ My GitHub Repo for t
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Victor Gayral: From equivariant quantization to locally compact quantum group ...
Full Title: From equivariant quantization to locally compact quantum group via deformation of C*-algebras The goal of this talk is to explain how non-formal equivariant quantization gives rise to a theory of deformation of C*-algebras and to concrete examples of locally compact quantum gr
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Polygenic Adaptation by Kavita Jain
DISCUSSION MEETING SECOND PREPARATORY SCHOOL ON POPULATION GENETICS AND EVOLUTION ORGANIZERS Deepa Agashe (NCBS-TIFR, India) and Kavita Jain (JNCASR, India) DATE: 20 February 2023 to 24 February 2023 VENUE Madhava Lecture Hall, ICTS Bengaluru We plan an intensive 1-week preparatory school
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TAS Kabuki Quantum Fighter NES in 9:20 by Nitsuja
Tool-Assisted http://tasvideos.org Played in 09:20.83 by JSP (aka. Nitsuja). This is a tool-assisted speedrun. For further informations visit http://tasvideos.org/467M.html
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Maximal Flows and Minimal Cutsets in First Passage Percolation in $\mathbb Z^d$ by Barbara Dembin
PROGRAM: PROBABILISTIC METHODS IN NEGATIVE CURVATURE (ONLINE) ORGANIZERS: Riddhipratim Basu (ICTS - TIFR, Bengaluru), Anish Ghosh (TIFR, Mumbai) and Mahan M J (TIFR, Mumbai) DATE & TIME: 01 March 2021 to 12 March 2021 VENUE: Online Due to the ongoing COVID pandemic, the meeting will
From playlist Probabilistic Methods in Negative Curvature (Online)
TAS Final Fantasy 5 SNES in 214:41 by samurai goroh
Tool-Assisted http://tasvideos.org Played in 3:34:41.07 by Erick Guillen aka. samurai goroh. This is a tool-assisted speedrun. For further informations visit http://tasvideos.org/942M.html
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