Structure-based combinatorial protein engineering (SCOPE) is a synthetic biology technique for creating gene libraries (lineages) of defined composition designed from structural and probabilistic constraints of the encoded proteins. The development of this technique was driven by fundamental questions about protein structure, function, and evolution, although the technique is generally applicable for the creation of engineered proteins with commercially desirable properties. Combinatorial travel through sequence spacetime is the goal of SCOPE. (Wikipedia).
Everyone has heard of proteins. What are they on the molecular level? They're polymers of amino acids, of course. They make up most of your body, so we have to understand their structure very well! Check this out to learn the hierarchy of protein structure so that we can later learn all ab
From playlist Biochemistry
Protein Structure - Primary, Secondary, Tertiary, & Quarternary - Biology
This biology video tutorial provides a basic introduction into the four levels of protein structure - primary, secondary, tertiary and quarternary structure. The primary structure of a protein is based on the sequence of amino acids. The secondary structure is based on localized shapes s
From playlist Biochemistry
To start using Tab for a Cause, go to: http://tabforacause.org/minuteearth2 You might already know that proteins are a fundamental part of your diet, but they're much more than that. LEARN MORE ************** To learn more about this topic, start your googling with these keywords: - Amino
From playlist Biology
What Are Proteins | Cells | Biology | FuseSchool
CREDITS Design and animation: Reshenda Wakefield Narration: Dale Bennett Script: Bethan Parry In this video, we are going to discuss the structure and uses of protein molecules. Proteins are long-chain molecules made of strings of amino acids joined together. All amino acids are compoun
From playlist BIOLOGY
Bruno Correia - Exploring new molecular representations for the design of biological function
Recorded 26 January 2023. Bruno Correia of the École Polytechnique Fédérale de Lausanne presents "Exploring new molecular representations for the design of biological function" at IPAM's Learning and Emergence in Molecular Systems Workshop. Abstract: Finely orchestrated protein activities
From playlist 2023 Learning and Emergence in Molecular Systems
R1. Determining, Analyzing, and Understanding Protein Structures
MIT 5.08J Biological Chemistry II, Spring 2016 View the complete course: https://ocw.mit.edu/5-08JS16 Instructor: Shiva Mandala This recitation covers different techniques that are used to determine protein structure, as well as using the Protein Data Bank (PDB). Students then complete a
From playlist MIT 5.08J Biological Chemistry II, Spring 2016
2012 Breakthrough Runner-Up: X-Ray Crystallography
For the first time, scientists determined the structure of a protein using an x-ray laser—even as the laser blasted tiny crystals of the stuff to bits. Powered by linear accelerators, x-ray lasers can work with crystals too small to be studied with synchrotons, paving the way toward eventu
From playlist Breakthrough of the Year
7A. Protein 1: 3D Structural Genomics, Homology, Catalytic and Regulatory Dynamics, Fun...
MIT HST.508 Genomics and Computational Biology, Fall 2002 Instructor: George Church View the complete course: https://ocw.mit.edu/courses/hst-508-genomics-and-computational-biology-fall-2002/ YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61gaHWysmlYNeGsuUI8y5GV Today
From playlist HST.508 Genomics and Computational Biology, Fall 2002
10. Structure-based feature vector
Chemistry alone isn't enough to help ML models make predictions. Instead, we need to featurize the structure of a material. What aspects would make good structural features? How do we featurize them? This video covers some relevant structural features from the atomic through the crystal st
From playlist Materials Informatics
MIT 7.013 Introductory Biology, Spring 2011 View the complete course: http://ocw.mit.edu/7-013S11 Instructor: Hazel Sive Professor Sive discusses cell types and explains how they differentiate. License: Creative Commons BY-NC-SA More information at http://ocw.mit.edu/terms More courses a
From playlist MIT 7.013 Introductory Biology, Spring 2011
22. Causality, Natural Computing, and Engineering Genomes
MIT 7.91J Foundations of Computational and Systems Biology, Spring 2014 View the complete course: http://ocw.mit.edu/7-91JS14 Instructor: George Church This guest lecture by Prof. George Church is on the topic of causality, in particular, how to use genomic data and the tools of natural c
From playlist MIT 7.91J Foundations of Computational and Systems Biology
Interdisciplinarity in the Age of Networks - Jennifer Chayes
Jennifer Chayes Managing Director, Microsoft Research New England, Microsoft Research New York May 21, 2013 For more videos, visit http://video.ias.edu
From playlist Mathematics
Kyunghyun Cho - Lab-in-the-loop de novo antibody design - what are we missing from machine learning?
Recorded 25 January 2023. Kyunghyun Cho of New York University presents "Lab-in-the-loop de novo antibody design - what are we missing from machine learning?" at IPAM's Learning and Emergence in Molecular Systems Workshop. Abstract: In this talk, I will give an overview of what we do at Pr
From playlist 2023 Learning and Emergence in Molecular Systems
Keynote: AI for Adaptive Experiment Design - Yisong Yue - 10/25/2019
AI-4-Science Workshop, October 25, 2019 at Bechtel Residence Dining Hall, Caltech. Learn more about: - AI-4-science: https://www.ist.caltech.edu/ai4science/ - Events: https://www.ist.caltech.edu/events/ Produced in association with Caltech Academic Media Technologies. ©2019 California I
From playlist AI-4-Science Workshop
Genetic conflicts between and within genomes (Lecture - 02) by Harmit Malik
Winter School on Quantitative Systems Biology DATE:04 December 2017 to 22 December 2017 VENUE:Ramanujan Lecture Hall, ICTS, Bengaluru The International Centre for Theoretical Sciences (ICTS) and the Abdus Salam International Centre for Theoretical Physics (ICTP), are organizing a Winter S
From playlist Winter School on Quantitative Systems Biology
Jennifer Tour Chayes (Microsoft Research New England and Microsoft Research New York City) URL: https://www.icts.res.in/lecture/4/details/1644/ Description: Everywhere we turn these days, we find that networks can be used to describe relevant interactions.In the high tech world, we see th
From playlist Distinguished Lectures
Ribosomal and chaperone proteins
More Info: http://www.caltech.edu/news/protein-chaperone-takes-its-job-seriously-53902 A chaperone protein binds to a ribosomal protein in a manner that protects the ribosomal protein from degradation by the cell’s liquidation machinery. When the chaperone protein releases the ribosomal p
From playlist Our Research
Konstantin Mischaikow (1/27/21): Nonlinear Dynamics in an Age of Heuristic Science
Title: Nonlinear Dynamics in an Age of Heuristic Science Abstract: Motivated by problems in systems and synthetic biology (but I believe the problems are common to multiscale systems and data driven science) I will argue the need for a new framework in which to discuss nonlinear dynamics
From playlist AATRN 2021
A Level Biology Revision "Amino Acids"
In this video, we look at amino acids. We start by looking at the general structure of amino acids and then look at two specific examples. We then explore how amino acids can be joined by forming a peptide bond in a condensation reaction and how the peptide bond can be broken by hydrolysis
From playlist A Level Biology Biological Molecules