The first phenotypic disease network was constructed by Hidalgo et al. (2009) to help understand the origins of many diseases and the links between them. Hidalgo et al. (2009) defined diseases as specific sets of phenotypes that affect one or several physiological systems, and compiled data on pairwise comorbidity correlations for more than 10,000 diseases reconstructed from over 30 million medical records. Hidalgo et al. (2009) presented their data in the form of a network with diseases as the nodes and comorbidity correlations as the links. Intuitively, the phenotypic disease network (PDN) can be seen as a map of the phenotypic space whose structure can contribute to the understanding of disease progression. (Wikipedia).
Watch more videos on http://www.brightstorm.com/science/biology SUBSCRIBE FOR All OUR VIDEOS! https://www.youtube.com/subscription_center?add_user=brightstorm2 VISIT BRIGHTSTORM.com FOR TONS OF VIDEO TUTORIALS AND OTHER FEATURES! http://www.brightstorm.com/ LET'S CONNECT! Facebook ► htt
From playlist Biology
Chloé Azencott: Network-guided feature selection in high-dimensional genomic data
Differences in disease predisposition or response to treatment can be explained in great part by genomic differences between individuals. This has given birth to precision medicine, where treatment is tailored to the genome of patients. This field depends on collecting considerable amounts
From playlist Probability and Statistics
Science Bulletins: Genes and Health—Moving Beyond Race
Many diseases have both genetic and environmental causes. Scientists often take traditional racial boundaries into account when researching why certain populations seem predisposed to certain diseases. But work on asthma at the University of California--San Francisco is going beyond curren
From playlist Science Bulletins
Neurotransmitters: Type, Structure, and Function
We know that neurotransmitters are signaling molecules that travel across the synaptic space to interact with receptors and propagate signals from one neuron to the next. But what are these molecules? What are their structures? How do they work? Let's get a closer look! Watch the whole Bi
From playlist Biopsychology
Ruedi Aebersold - The proteome in context
The question how genetic variability is translated into phenotypes is fundamental in biology and medicine. Powerful genomic technologies now determine genetic variability at a genomic level and at unprecedented speed, accuracy and (low) cost. Concurrently, life style monitori
From playlist From Molecules and Cells to Human Health : Ideas and concepts
Epigenetik - Änderungen jenseits des genetischen Codes
Kleine chemische Anhängsel an der DNA und den Histon-Verpackungsproteinen kontrollieren die Aktivität von Genen. Sie wirken wie Schalter, die Gene an- und abschalten können. Material für die Schule: Biomax 23: Epigenetik https://www.max-wissen.de/max-hefte/biomax-23-epigenetik/
From playlist Most popular videos
Ting Zhang - Recombinant DENV 2 NS5: An Effective Antigen for Diagnosis of Dengue Infection
Dengue fever as one of the most important mosquito-borne disease worldwide which approximately half of the world's population is at risk presenting several degrees of symptoms, including life-threatening dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS). Deng
From playlist From Molecules and Cells to Human Health : Ideas and concepts
Glucocorticoids: Mechanisms and Side Effects
Glucocorticoids constitute a major drug class in treating inflammation and autoimmune disease. These include endogenous hormones that can be administered exogenously, but also synthetic alternatives with a variety of functions. These drugs interact with the glucocorticoid receptor, but wha
From playlist Pharmacology
Research talks by Himanshu Sinha
Second Bangalore School on Population Genetics and Evolution URL: http://www.icts.res.in/program/popgen2016 DESCRIPTION: Just as evolution is central to our understanding of biology, population genetics theory provides the basic framework to comprehend evolutionary processes. Population
From playlist Second Bangalore School on Population Genetics and Evolution
CS224W: Machine Learning with Graphs | 2021 | Lecture 18 - GNNs in Computational Biology
For more information about Stanford’s Artificial Intelligence professional and graduate programs, visit: https://stanford.io/2XVImFC Lecture 18 - Graph Neural Networks in Computational Biology Jure Leskovec Computer Science, PhD We are glad to invite Prof. Marinka Zitnik from Harvard Un
From playlist Stanford CS224W: Machine Learning with Graphs
Dynamical systems biology of cancer metastasis by Mohit Kumar Jolly
DISCUSSION MEETING : MATHEMATICAL AND STATISTICAL EXPLORATIONS IN DISEASE MODELLING AND PUBLIC HEALTH ORGANIZERS : Nagasuma Chandra, Martin Lopez-Garcia, Carmen Molina-Paris and Saumyadipta Pyne DATE & TIME : 01 July 2019 to 11 July 2019 VENUE : Madhava Lecture Hall, ICTS, Bangalore
From playlist Mathematical and statistical explorations in disease modelling and public health
Watch more videos on http://www.brightstorm.com/science/biology SUBSCRIBE FOR All OUR VIDEOS! https://www.youtube.com/subscription_center?add_user=brightstorm2 VISIT BRIGHTSTORM.com FOR TONS OF VIDEO TUTORIALS AND OTHER FEATURES! http://www.brightstorm.com/ LET'S CONNECT! Facebook ► htt
From playlist Biology
Making the most of imaging data: Declan O'Regan, Imperial College London
About the event This workshop is being held in association with a new call for applications for joint research awards in Cardiovascular Data Science by the British Heart Foundation (BHF) and The Alan Turing Institute (the Turing). The awards aim to support cross-disciplinary teams of inve
From playlist Exploring novel opportunities for data science in cardiovascular research
Charlie Boone - The Genetic Landscape of a Cell
We generated a global genetic interaction network for Saccharomyces cerevisiae, testing most of the 18 million possible gene pairs for genetic interactions, identifying ~550,000 negative and ~350,000 positive genetic interactions. This comprehensive network maps genetic intera
From playlist From Molecules and Cells to Human Health : Ideas and concepts
Su-In Lee: "Interpretable Machine Learning for Precision Medicine"
Computational Genomics Winter Institute 2018 "Interpretable Machine Learning for Precision Medicine" Su-In Lee, University of Washington Institute for Pure and Applied Mathematics, UCLA March 2, 2018 For more information: http://computationalgenomics.bioinformatics.ucla.edu/programs/201
From playlist Computational Genomics Winter Institute 2018
The Emergence of Proactive P4 Medicine: A Revolution in Healthcare - Leroy Hood
Dr. Leroy Hood with the Institute of Systems Biology will focus on their efforts at taking a systems approach to diseases—looking at a neurodegenerative (prion) disease, PTSD and a brain tumor (glioblastoma) in mice and humans. The mouse models allows them to analyze the initiation and pro
From playlist Strata Rx
A Level Biology Revision "Neutrophils, Macrophages and Phagocytosis"
In this video, we look at neutrophils, macrophages and phagocytosis. First we explore the different categories of white blood cells. We then look at how neutrophils carry out phagocytosis and the role of opsonins. Then, we explore the role of macrophages as antigen-presenting cells. Finall
From playlist A Level Biology "Infectious Diseases and the Immune System"
Ran Blekhman: "Human genomic control of the microbiome"
Computational Genomics Summer Institute 2017 Research Talk: "Human genomic control of the microbiome" Ran Blekhman, University of Minnesota Institute for Pure and Applied Mathematics, UCLA July 12, 2017 For more information: http://computationalgenomics.bioinformatics.ucla.edu/
From playlist Computational Genomics Summer Institute 2017