Acetaminophen/Paracetamol (Tylenol)
Acetaminophen, more commonly known by brand names such as Tylenol, is not a true NSAID, as it does not have anti-inflammatory properties. However, it is commonly discussed alongside NSAIDs as it has similar antipyretic and analgesic properties. Although its mechanism of action is not well-
From playlist Pharmacology
Synthesis of a Bromoalkane (n-Bromopropane)
In this video, I will be making n-bromopropane by brominating 1-propanol. The n-bromopropane can then be used in a Grignard reaction to make butyric acid (smell of vomit). Here is the video of me using it in a Grignard reaction: http://youtu.be/_wmx65zQk58 This process can be used as a
From playlist Syntheses and Demonstrations
We know how to do acid-catalyzed hydration, which is a Markovnikov hydration, but there is another way to do this, one that does not result in carbocation rearrangement. Let's look at the mechanism and application of oxymercuration-demercuration. Watch the whole Organic Chemistry playlist
From playlist Organic Chemistry
In this video we make a chemiluminescent reaction that is activated by a vapor. The reaction is very easy to perform: Mix 3mL of dimethyl phthalate, 3mg of fluorescent dye such as rubrene, and 3mL of hydrogen peroxide (30%) and shake. Let the mixture separate and apply the bottom dimethyl
From playlist Glow Science
Making glow sticks from scratch
Signup for your FREE trial to The Great Courses Plus here: http://ow.ly/rqYQ30db4OA "The Great Courses Plus is currently available to watch through a web browser to almost anyone in the world and optimized for the US market. The Great Courses Plus is currently working to both optimize the
From playlist Everyday chemicals
Oxidations - DMP, PCC & Swern - Aldehydes & Ketones (IOC 24)
In this episode, I discuss oxidations with DMP, PCC, and Swern. Aldehydes are reactive intermediates, and methods for their synthesis are important! ---------------------------------------------------------------------------------------------------------------------------------- Links to
From playlist Organic Chemistry Lectures
Aspirin (Acetylsalicylic Acid)
Now that we understand the basics regarding NSAIDs, let's dive into a few specific drugs from this class. First up, aspirin. This drug has been around for centuries, but now with a modern understanding of chemistry and biochemistry, we are able to understand its precise structure and mecha
From playlist Pharmacology
How to make TCPO (for making glow sticks)
How to make TCPO or bis(2,4,6-trichlorophenyl) oxalate, used in glow stick reactions. WARNING: This procedure should only be performed by, or under the direct supervision of, an experienced chemist. Please refer to the material safety data sheets of all chemicals for their hazards. Synthe
From playlist Glow Science
In the world of chemistry, an "organic" compound is often described as anything with carbon in it, and "organic chemistry" is the study of carbon compounds, but there is actually no single definition of what "organic" means in chemistry, and scientists have been arguing about it for a long
From playlist Uploads
Ethyl Chloroacetate a Deadly Precursor to Many Pharmaceuticals
In this video ethyl chloroacetate which is a precursor to many pharmaceuticals will be prepared. We will make it by doing an esterification reaction involving chloroacetic acid, ethanol, sulfuric acid and a lot of patience. Ethyl chloroacetate is a toxic liquid used to make chloroacetamide
From playlist Organic Chemistry
Making Phosphorus Pentachloride: A Powerful Chlorinating Agent (TCPO 2/5)
This is video 2/5 on making TCPO (active ingredient in glow sticks) from scratch. Labcoatz channel: https://www.youtube.com/channel/UCcT_WBynr2K8nANsVrR8BYw?app=desktop Patreon: https://www.patreon.com/thyzoid Discord: https://discord.gg/UrjAt44HWH (Let me know if the discord link does n
From playlist Inorganic Chemistry
Swern Oxidation - Organic Chemistry, Reaction Mechanism
My commentary on the mechanism of a Swern oxidation, a widely used transformation in organic chemistry. I also outline my favourite sneaky use of the mechanism when oxidising 1,5-diols to 1,5-dicarbonyls. #chemistry #orgo #ochem #mechanism #synthesis The Swern oxidation is a mild oxidati
From playlist Organic Chemistry Mechanisms
Base Hydrolysis of Benzonitrile
CSUN Chemistry and Biochemistry department 2nd Semester Organic Chemistry Lab Base Hydrolysis of Benzonitrile Demonstration of why we cool reaction: https://www.youtube.com/watch?v=csWxoRBSUVk Ref: Chem 334 lab manual spring 2016 L.G. Wade, Organic Chem 8th made by Benjamin D Azmon
From playlist 334L OChem 2
Staudinger Reactions - Bioothogonal before Click Chemistry
The original bioorthogonal chemistry using azides and their reaction phosphines to form aza-ylids, which can do bioconjugation reactions and other useful transformations in organic synthesis. The aza-ylid (aminophosphorane) generated can react directly with water in a hydrolysis reaction
From playlist Organic Chemistry Mechanisms
Sorry, the shirts shown in this video are no longer available, but there are still cool things like pins and keychains: https://nilered.tv/store ------------------------------------------- If metal has no odor and you can't smell it, then what are we smelling? It turns out that it's mos
From playlist Interesting Explanations
Get a free 30-day Audible trial today by signing up at http://www.audible.com/nilered -------------------------------- Note: I write cyclohexanol in the video, but it is actually cyclohexane that I used. I also wrote in the comments it was cyclohexanol...so double mistake. oops In this v
From playlist Everyday chemicals
Oxidative Cleavage of Alkenes & Alkynes - KMnO4 & Ozonolysis (IOC 27)
In this episode, I discuss the oxidative cleavage of alkenes and alkynes, using KMnO4 and ozone. Here is the video from ChemicalForce featuring liquid ozone: https://www.youtube.com/watch?v=vttsvMKQ1Yw *WARNING* ozone is very toxic, and ozonides can be explosive! Great care should be tak
From playlist Organic Chemistry Lectures
From playlist Organic Chemistry
Total Synthesis of (+)-Cochlearol B
An organic chemistry minilecture on the Total Synthesis of (+)-Cochlearol B by an Approach Based on a Catellani Reaction and Visible-Light-Enabled [2+2] Cycloaddition by Alistair D. Richardson, Trenton R. Vogel, Emily F. Traficante, Kason J. Glover, and Corinna S.Schindler*. Highlights inc
From playlist Total Synthesis
We gotta know how to name all the molecules, and oxyacids are a type of molecule, so let's learn how to name them! Watch the whole General Chemistry playlist: http://bit.ly/ProfDaveGenChem Organic Chemistry Tutorials: http://bit.ly/ProfDaveOrgChem Biochemistry Tutorials: http://bit.ly/Pr
From playlist General Chemistry