Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary in size and cost, and they can involve a single research center or multiple centers, in one country or in multiple countries. Clinical study design aims to ensure the scientific validity and reproducibility of the results. Costs for clinical trials can range into the billions of dollars per approved drug. The sponsor may be a governmental organization or a pharmaceutical, biotechnology or medical device company. Certain functions necessary to the trial, such as monitoring and lab work, may be managed by an outsourced partner, such as a contract research organization or a central laboratory. Only 10 percent of all drugs started in human clinical trials become approved drugs. (Wikipedia).
Research Studies Could Be More Pragmatic, and More Useful
Subscribe to Healthcare Triage! https://bit.ly/2GlEYWG Promising health studies often don’t pan out in reality. The reasons are many. Research participants are usually different from general patients; their treatment doesn’t match real-world practice; researchers can devote resources not
From playlist Research
Testing and Online Experimentation
Join Data Science Dojo and Statsig for a conversation on experimentation and testing. Learn how leading companies like Facebook use experimentation to build better products and accelerate their growth with 10x as much testing. Web experimentation can range from simple projects like design
From playlist A/B Testing & Beyond
Pharmaceutical Drugs: Inhibitors and the Nature of Disease
We live in a time where there is much skepticism towards modern medicine. This stems purely from ignorance, however, and there are those who capitalize on this to sell an unbelievable array of alternative medicines that, almost without exception, do absolutely nothing. Let's take a look at
From playlist Biochemistry
What are Some of the Treatment Options for Breast Cancer?
MEDICAL ANIMATION TRANSCRIPT: Breast cancer is a disease where some of the cells in the breast begin to grow uncontrollably. Treatments for breast cancer can include surgery, radiation therapy, chemotherapy, hormone therapy, targeted therapy, and immunotherapy. There are several types of
From playlist Healthcare Patient Education Animations
Building A Product From The Ground Up
For most seasoned business owners and aspiring entrepreneurs, the product development process often carries a mystical aura. Product development refers to the complete process of taking a product to market. It also covers renewing an existing product and introducing an old product to a new
From playlist Product Development
What is a Statistical Treatment?
What is a statistical treatment? How to choose a statistical test. 0:00 Intro 00:19 Data Analysis 00:55 Choosing hypothesis tests 2:58 Factor Analysis 3:23 Thesis / Experimental View the flowchart here: https://www.datasciencecentral.com/profiles/blogs/hypothesis-tests-in-one-picture
From playlist Hypothesis Tests and Critical Values
Parametric and nonparametric tests
Parametric tests are most commonly used in healthcare research. They include tests such as Student's t-test and ANOVA. There is, however a rich set of non-parametric tests that are much more appropriate to use in certain circumstances.
From playlist Learning medical statistics with python and Jupyter notebooks
3_1 Introduction to Antibiotics
An introduction to the talks on the use of antibiotics in surgical practice.
From playlist Surgery Intermediate Exam Masterclass
NLP for Clinical Excellence: The State of Practices, Opportunities, and Challenges
Presented by: Yanshan Wang - Vice Chair of Research and Assistant Professor at University of Pittsburgh Rapid growth in adoption of electronic health records (EHRs) has led to an unprecedented expansion in the availability of large longitudinal datasets Large initiatives such as the Elect
From playlist Healthcare NLP Summit 2022
Bandit Problems and Ethical Clinical Trials - William Press
William Press The University of Texas at Austin September 28, 2013 More videos on http://video.ias.edu
From playlist Dreams of Earth and Sky
Text Analytics and its Applications in the Pharma Industry | NLP Summit 2020
Get your Free Spark NLP and Spark OCR Free Trial: https://www.johnsnowlabs.com/spark-nlp-try-free/ Register for NLP Summit 2021: https://www.nlpsummit.org/2021-events/ Watch all NLP Summit 2020 sessions: https://www.nlpsummit.org/ In the healthcare domain, the product life cycle from t
From playlist NLP Summit 2020
James Zou: Trust is AI’s most critical contribution to health care
Subscribe to Stanford Engineering's The Future of Everything podcast: https://the-future-of-everything-stanford-engineering.simplecast.com/ AI can reveal remarkable medical insights, but only if patients and doctors have faith in it. Thus, trust has become AI’s singular goal, says this ex
From playlist The Future of Everything
The Big Problem With The Drugs You Take
Who makes sure the drugs you take are safe, and can you trust them? TAKE THIS SURVEY! (sponsored link): http://bit.ly/LifeNoggin Subscribe: https://bit.ly/SubLifeNoggin | Get your exclusive Life Noggin merch: http://keeponthinking.co Support Life Noggin on Patreon: https://patreon.com/
From playlist Popular Uploads | Life Noggin
Lesson Learned annotating training data for healthcare NLP projects | NLP Summit 2020
Try 50+ pre-trained entity recognition models including signs & symptoms, diagnoses, procedures, anatomy, demographics, risk factors, vitals, labs, and more. Use 15+ image processing algorithms for OCR from low-quality documents. Looking forward to your feedback! In lessons learned anno
From playlist NLP Summit 2020
Cancer Cure Cover-Up? (Conspiracy Documentary) | Real Stories
The modern biographical story of Stanislaw Burzynski, MD, PhD who discovered an innovative patent-protected cancer therapy currently enrolled in FDA clinical trials. This story sheds light on the current regulatory and industry roadblocks preventing these life-saving medications from reach
From playlist Medical Stories
Translational Medicine: From Better Ideas to Better Health
Dr. Robert M. Califf talks about translational medicine, in one of a series of lectures from The Yale School of Medicine Bicentennial Symposium, "Biomedicine in the New Century," which took place over April 28--29, 2011.
From playlist The Yale School of Medicine Bicentennial Symposium
Yale AIDS Colloquium Series - Sarah Calabrese
"Prescribing Pre-Exposure Prophylaxis for HIV Prevention: Barriers and Biases among Healthcare Providers" HIV pre-exposure prophylaxis (PrEP) has emerged as a promising biomedical prevention strategy for people at high risk for HIV acquisition. However, its establishment has been met by
From playlist Center for Interdisciplinary Research on AIDS
Let Your Users Decide What They Want (Power of A/B Tests)
My talk is about letting the users help you understand what they need and if a particular feature is really useful for the users by using the technique of A/B testing. We are constantly running A/B tests to improve the customer experience by measuring the business metrics. Attend my talk t
From playlist Performance and Testing
Is There Any Actual Science Behind Stem Cell Therapy?
Stem cell research promises incredible cures, but what are the risks and how successful are these trials really? Reprogramming Skin to Grow New Organs Is Now Possible - https://youtu.be/6txIbBQGu5k Read More: Three Women Blinded By Unapproved Stem-cell ‘treatment’ At South Florida Cli
From playlist Elements | Seeker