Azanide is the IUPAC-sanctioned name for the anion NH−2. The term is obscure; derivatives of NH−2 are almost invariably referred to as amides, despite the fact that amide also refers to the organic functional group –C(=O)−NR2. The anion NH−2 is the conjugate base of ammonia, so it is formed by the self-ionization of ammonia. It is produced by deprotonation of ammonia, usually with strong bases or an alkali metal. Azanide has a H–N–H bond angle of 104.5°. (Wikipedia).
Aspirin (Acetylsalicylic Acid)
Now that we understand the basics regarding NSAIDs, let's dive into a few specific drugs from this class. First up, aspirin. This drug has been around for centuries, but now with a modern understanding of chemistry and biochemistry, we are able to understand its precise structure and mecha
From playlist Pharmacology
This one is for all the homechemists out there, finally something u might be able to replicate!! Support my channel with patreon: https://www.patreon.com/chemiolis Support my channel by becoming a member https://www.youtube.com/channel/UCoDmZirW1o9XSKSRM6YJ1rQ/join
From playlist Chemistry for home-labs and self-production
Staudinger Reactions - Bioothogonal before Click Chemistry
The original bioorthogonal chemistry using azides and their reaction phosphines to form aza-ylids, which can do bioconjugation reactions and other useful transformations in organic synthesis. The aza-ylid (aminophosphorane) generated can react directly with water in a hydrolysis reaction
From playlist Organic Chemistry Mechanisms
Molecular Orbitals of the Azide Anion (Physical Chemistry)
A way of thinking about constructing a qualitative MO diagram for the azide anion. #chemistry #physicalchemistry #physics #pchem #quantum #orbitals #electrons #symmetry ---------- When considering the molecular orbitals of a polyatomic system, it is usually easiest when there is a lot o
From playlist Random Physical Chemistry
Destroying 10 grams of tosyl azide
Here is an uncut video of quenching 10 grams of tosyl azide using acetylacetone and sodium hydroxide in water/acetonitrile followed by the decomposition of diazoacetone with sodium nitrite and sulfuric acid. I decided that storing tosyl azide which was over one year old was unsafe and tha
From playlist Rad Chemistry Experiments